NAD+

NAD+

500mg
£50.00
£50.00
Skip to product information
NAD+
  • NAD+
  • NAD+
NAD+

NAD+

£50.00
£50.00
Size
For Research Purposes Only — Not For Human Use This product is intended solely for laboratory and in-vitro research. Not for human consumption, medical use, or self-administration.
Third-party tested
1–2 day tracked dispatch
Discreet packaging
99%+ purity guaranteed
For Research Use OnlyThis compound is strictly for laboratory and in-vitro research. Not for human consumption or medical use.
Reconstitution
Pen format? Pens are supplied pre-mixed and ready for research use — no reconstitution required. The steps below apply to lyophilized vials only.
  1. Swab both vial stoppers with alcohol and allow to dry.
  2. Draw the required volume of bacteriostatic water with a sterile syringe.
  3. Add the water slowly down the inside wall of the vial — never directly onto the powder.
  4. Swirl gently until fully dissolved. Never shake.
  5. Confirm the solution is clear and particle-free.
  6. Label with date and concentration, then refrigerate at 2–8 °C.
Full guide & dose calculator
Storage & Handling
  • Lyophilized vials: refrigerate sealed at 2–8 °C away from light; freeze at −20 °C for storage beyond 6 months.
  • After reconstitution: refrigerate at 2–8 °C; typically stable 4–8 weeks with bacteriostatic water. Do not freeze once mixed.
  • Pre-mixed pens: arrive ready to use — refrigerate at 2–8 °C with the cap on and never freeze.
  • General: avoid direct sunlight, heat and repeated temperature swings; minimise agitation.
Quality & Shipping FAQ
  • Is this compound tested? Yes — every batch is third-party tested by accredited labs (HPLC & mass spectrometry) at 99%+ verified purity.
  • How is it supplied? As lyophilized powder in a sealed sterile vial (or pre-mixed pen where offered), with research-use labelling.
  • How fast is dispatch? 1–2 working day dispatch, 2–3 days UK delivery, in plain discreet packaging.
  • What is it for? Strictly laboratory and in-vitro research — not for human or veterinary consumption, medical use or self-administration.
View the peer-reviewed research
Packaging update Our branded boxes are temporarily out of stock. Until new stock lands, orders ship in plain, discreet packaging — the same product inside, sealed and dispatched with the same care. Thank you for your patience.

NAD+ (Nicotinamide Adenine Dinucleotide)

NAD+ is a coenzyme found in all living cells, central to cellular energy metabolism and redox reactions. It is a major focus of ageing and metabolic research.

About the compound

In laboratory research, NAD+ is studied for its role in cellular energy production, redox balance, DNA-repair pathways and sirtuin signalling. Cellular NAD+ levels are known to decline with age, making it a frequent subject of metabolic and ageing research in cell and animal models.

Specifications

  • Purity: 99%+ (third-party verified)
  • Independently tested before dispatch
  • Presented as lyophilised (freeze-dried) powder
  • Supplied for in-vitro laboratory research only

FAQ

Is it tested? Yes — every batch is independently tested to 99%+ purity before dispatch.
What form does it arrive in? Lyophilised powder.
What is this sold for? Laboratory and research use only. Not for human or animal consumption.

⚖ For Laboratory Research Use Only — Not for Human Consumption.
Peer-Reviewed Evidence

Research & Studies

Independent published research on NAD+

NAD+ Cellular Biology Human RCT

NAD+ Precursor Supplementation Improves Muscle Insulin Sensitivity in Human Participants

Science · Yoshino et al., 2021

The first human RCT demonstrating metabolic benefits of NAD+ precursor supplementation: 25 postmenopausal women with prediabetes received NMN for 10 weeks. NMN significantly increased skeletal muscle NAD+ levels, enhanced insulin sensitivity by hyperinsulinaemic-euglycaemic clamp, and upregulated muscle remodelling and mitochondrial genes. These findings in humans directly support the mechanistic role of NAD+ depletion in insulin resistance.

Human RCT Insulin Sensitivity Skeletal Muscle
NAD+ Longevity Human RCT

NAD+ Supplementation Increases Walking Speed and Improves Muscle Function in Older Adults

Nature Aging · Igarashi et al., 2022

A 12-week randomised, double-blind, placebo-controlled trial in older adults administered NMN (250mg/day). NMN significantly increased blood NAD+ levels, and in participants who exercised regularly, significantly improved gait speed, grip strength, and performance on the 30-second chair stand test. Gene expression analysis showed upregulation of muscle remodelling pathways and mitochondrial function genes. These findings in humans confirm NAD+ supplementation translates preclinical longevity findings into measurable functional improvements in ageing skeletal muscle.

Human RCT Muscle Function Healthy Ageing
NAD+ / NMN Metabolic Research Human RCT

Nicotinamide Mononucleotide Increases Muscle Insulin Sensitivity in Prediabetic Women

Science · Yoshino et al., 2021

A 10-week randomised, double-blind, placebo-controlled trial of oral NMN (250 mg/day), a direct NAD+ precursor, in postmenopausal women with prediabetes. NMN raised NAD+ metabolites in skeletal muscle and improved muscle insulin sensitivity by approximately 25%, with enhanced insulin signalling and muscle remodelling — the first human evidence of a metabolic benefit from NMN supplementation.

NAD+ Precursor Insulin Sensitivity Human RCT
NAD+ Cellular Biology Animal Model

NAD&sup+;: Therapeutic Potential of NAD-Boosting Molecules in Ageing and Cellular Energy Research

Cell Metabolism · Rajman, Chwalek & Sinclair, 2018

Nicotinamide adenine dinucleotide (NAD&sup+;) is an essential coenzyme central to cellular energy metabolism and a key substrate for sirtuin deacylases and poly(ADP-ribose) polymerases (PARPs). A landmark review catalogued in-vivo evidence demonstrating that restoring NAD&sup+; levels reverses multiple hallmarks of biological ageing in preclinical models. Research showed NAD&sup+; depletion associates with mitochondrial dysfunction and impaired DNA repair, while restoration activates sirtuins and promotes mitochondrial biogenesis.

Sirtuins PARP Mitochondrial Biogenesis
View the full research library →

You may also like