Research peptides are manufactured, not extracted. This article introduces how peptides are made in the laboratory.
What is a peptide?
A peptide is a short chain of amino acids linked by peptide bonds. The specific sequence defines the peptide and its properties.
Solid-phase peptide synthesis (SPPS)
The dominant method is solid-phase peptide synthesis, a Nobel Prize–winning technique developed by Bruce Merrifield. Amino acids are added one at a time to a growing chain anchored to a solid resin, in a controlled, repeating cycle.
Purification
The crude peptide is then cleaved from the resin and purified — typically by preparative HPLC — to remove incomplete sequences and reach research-grade purity.
Verification
The finished peptide is analysed for identity (mass spectrometry) and purity (HPLC) before release. These results appear on the Certificate of Analysis.
At Peptide Pal
Our research peptides are third-party tested to 99%+ purity, with a COA per batch.
⚖ Supplied for laboratory research use only. Not for human or animal consumption.