GHK-Cu: A Research Overview

GHK-Cu is one of the most widely studied copper-binding peptides in dermatological and regenerative research. This overview explains what it is and the areas researchers investigate.

What is GHK-Cu?

GHK-Cu (copper tripeptide-1) is a naturally occurring tripeptide made of the amino acids glycine, histidine and lysine, bound to a copper ion. It occurs naturally in human plasma, and its concentration is known to decline with age.

Discovery

GHK was first identified in the 1970s as a factor in human plasma. Researchers later established its strong affinity for copper, forming the GHK-Cu complex that is the subject of most published studies.

Areas of research

In laboratory and in-vitro research, GHK-Cu has been studied in relation to:

  • Extracellular-matrix signalling and remodelling
  • Collagen and elastin gene expression in human dermal fibroblast models
  • Copper transport and delivery
  • Antioxidant-related pathways

Specifications at Peptide Pal

Our GHK-Cu is supplied as a lyophilised powder at 99%+ verified purity, with a Certificate of Analysis available for every batch.

⚖ Supplied for laboratory research use only. Not for human or animal consumption.