Mots-C

£25.00

Size 10mg 20mg

Type Vial Pen

Third-party tested

1–2 day tracked dispatch

Discreet packaging

99%+ purity guaranteed

For Research Use OnlyThis compound is strictly for laboratory and in-vitro research. Not for human consumption or medical use.

Reconstitution

Pen format? Pens are supplied pre-mixed and ready for research use — no reconstitution required. The steps below apply to lyophilized vials only.

Swab both vial stoppers with alcohol and allow to dry.
Draw the required volume of bacteriostatic water with a sterile syringe.
Add the water slowly down the inside wall of the vial — never directly onto the powder.
Swirl gently until fully dissolved. Never shake.
Confirm the solution is clear and particle-free.
Label with date and concentration, then refrigerate at 2–8 °C.

Full guide & dose calculator

Storage & Handling

Lyophilized vials: refrigerate sealed at 2–8 °C away from light; freeze at −20 °C for storage beyond 6 months.
After reconstitution: refrigerate at 2–8 °C; typically stable 4–8 weeks with bacteriostatic water. Do not freeze once mixed.
Pre-mixed pens: arrive ready to use — refrigerate at 2–8 °C with the cap on and never freeze.
General: avoid direct sunlight, heat and repeated temperature swings; minimise agitation.

Quality & Shipping FAQ

Is this compound tested? Yes — every batch is third-party tested by accredited labs (HPLC & mass spectrometry) at 99%+ verified purity.
How is it supplied? As lyophilized powder in a sealed sterile vial (or pre-mixed pen where offered), with research-use labelling.
How fast is dispatch? 1–2 working day dispatch, 2–3 days UK delivery, in plain discreet packaging.
What is it for? Strictly laboratory and in-vitro research — not for human or veterinary consumption, medical use or self-administration.

View the peer-reviewed research

Packaging update Our branded boxes are temporarily out of stock. Until new stock lands, orders ship in plain, discreet packaging — the same product inside, sealed and dispatched with the same care. Thank you for your patience.

MOTS-c

MOTS-c is a mitochondrial-derived peptide (encoded within the mitochondrial genome) that has become a notable subject of metabolic research.

About the compound

In published laboratory research, MOTS-c has been investigated for its role in cellular energy-regulation pathways — including studies examining AMPK-pathway signalling and metabolic homeostasis in cell and animal models. It is studied as a systemic metabolic signalling peptide.

Specifications

Purity: 99%+ (third-party verified)
Independently tested before dispatch
Presented as lyophilised (freeze-dried) powder
Supplied for in-vitro laboratory research only

FAQ

Is it tested? Yes — every batch is independently tested to 99%+ purity before dispatch.
What form does it arrive in? Lyophilised powder.
What is this sold for? Laboratory and research use only. Not for human or animal consumption.

⚖ For Laboratory Research Use Only — Not for Human Consumption.

Mots-C Longevity Human Subjects

Circulating MOTS-c Declines with Age and Correlates with Metabolic Health in Humans

Aging (Albany NY) · Kim et al., 2019

Researchers characterised MOTS-c as a detectable peptide in human blood and demonstrated a significant age-dependent decline in older adults. Individuals with high metabolic fitness maintained significantly elevated plasma MOTS-c, with levels correlating positively with insulin sensitivity, VO²max, and mitochondrial biogenesis markers. An exercise intervention arm showed plasma MOTS-c rose measurably within 30 minutes — confirming mitochondria release MOTS-c as a systemic endocrine signal in response to physiological energetic demand.

Human Subjects Exercise-Induced Mitochondrial Ageing

Mots-C Metabolic Research Animal Model

MOTS-c: Mitochondrial-Derived Peptide Regulation of Metabolic Homeostasis and Insulin Sensitivity

Cell Metabolism · Lee et al., 2015

MOTS-c is a 16-amino acid peptide encoded within the mitochondrial genome. Lee et al. demonstrated exogenous MOTS-c significantly reduced obesity and improved insulin sensitivity in rodent models, acting on skeletal muscle via the AMPK pathway to enhance glucose uptake and fatty acid oxidation. Subsequent human research confirmed circulating MOTS-c declines with age and correlates positively with insulin sensitivity, VO²max, and markers of mitochondrial biogenesis.

Mitochondrial Peptide AMPK Insulin Sensitivity

MOTS-c Cellular Biology Animal Model

MOTS-c Regulates Plasma Metabolites and Enhances Insulin Sensitivity

Physiological Reports · Kim et al., 2019

A study of the mitochondrial-derived peptide MOTS-c, a 16-amino-acid peptide encoded by mitochondrial DNA. MOTS-c injection improved whole-body insulin sensitivity by roughly 30% during hyperinsulinaemic clamp and reduced sphingolipid, monoacylglycerol and dicarboxylate metabolic pathways that are elevated in obesity and type-2 diabetes models, acting largely through AMPK activation in skeletal muscle.

Mitochondrial Peptide AMPK Insulin Sensitivity

MOTS-c Longevity Animal Model

MOTS-c Is an Exercise-Induced Regulator of Age-Dependent Physical Decline

Nature Communications · Reynolds et al., 2021

A study demonstrating that the mitochondrial-derived peptide MOTS-c is induced by exercise and regulates muscle homeostasis and age-dependent physical decline. In aged mice, MOTS-c treatment improved physical capacity and running performance, and the peptide translocated to the nucleus to regulate stress-adaptive genes — positioning it as a mitochondrial signal linking exercise to healthy ageing.

Exercise Mimetic Physical Capacity Healthy Ageing

View the full research library →